Medication-Related Osteonecrosis of the Jaw: What Dental Patients Should Know
Medication-related osteonecrosis of the jaw (MRONJ) is an uncommon but important condition associated with certain antiresorptive and antiangiogenic medications. Dental and medical teams consider medication history when planning invasive dental care.
Why medication history matters
Some medicines used for osteoporosis and some cancer treatments affect bone remodeling or blood-vessel pathways. The level of risk is not the same for every medication, dose, indication, or patient.
Tell your dentist before treatment
Provide an up-to-date medication list, including injections or infusions received outside the dental office. Do not stop a prescribed medication on your own because of a dental concern; decisions about medication changes belong with the prescribing clinician and dental team.
Prevention and coordination
Good oral hygiene, regular dental care, and treatment of active dental disease are important. When invasive treatment is being considered, the dentist may coordinate with the prescribing medical professional based on the individual situation.
Report concerning changes
Areas of exposed jaw bone, persistent pain or swelling, drainage, non-healing extraction sites, or unusual numbness should be evaluated by a dental professional.
Important: This page provides general education only. Medication decisions and dental treatment planning require individualized professional evaluation.
This article is general dental education and is not a diagnosis or a substitute for an examination. If you have pain, swelling, trauma, or another concern, contact a dental or medical professional as appropriate.
